Featured articles on Arthritis | Cannabinoid Treatment for Rheumatism: Greg Gerdeman, PhD

Arthritis is an inflammation of one or more of your joints. There are many different types, including osteoarthritis (OA) and rheumatoid arthritis (RA). Symptoms may include joint pain, stiffness, or swelling. About one in five people have arthritis. It is more common in women, and people with heart disease or diabetes.

Greg Gerdeman, former assistant professor of Biology at Eckerd College in St. Petersburg, Florida, spoke at the Annual Meeting of the Congress of Clinical Rheumatology. His remarks on cannabinoid treatment for rheumatic diseases can be heard here. Greg Gerdeman: “Using cannabis or other sources of cannabinoids for rheumatic diseases shows a lot of preclinical promise because of the importance of…

Dr. Ethan Russo: CBD & Clinical Endocannabinoid Deficiency

Dr. Ethan Russo, neurologist and medical scientist, discusses CBD, clinical endocannabinoid deficiency, and various ways to target the endocannabinoid system for therapeutic benefit.  Transcript Project CBD: Today we’re talking with Dr. Ethan Russo. Dr. Russo, a board certified neurologist, is the medical research director at Phytecs, a biotechnology company that specializes in developing…

Tale of Two Cannabinoids

Summary: This study examines the current knowledge of physiological and clinical effects of tetrahydrocannabinol (THC) and cannabidiol (CBD) and presents a rationale for their combination in pharmaceutical preparations. Cannabinoid and vanilloid receptor effects as well as non-receptor mechanisms are explored, such as the capability of THC and CBD to act as anti-inflammatory substances… Read more

Science abstracts on Arthritis

• Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis
• The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis
• Involvement of the endocannabinoid system in osteoarthritis
• The abnormal cannabidiol analogue O-1602 reduces nociception in a rat model of acute arthritis via the putative cannabinoid receptor GPR55
• Attenuation of early phase inflammation by cannabidiol prevents pain and nerve damage in rat osteoarthritis

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